| Mineral/rock | Derived from or for |
| Sanbornite | for Frank Sanborn, American mineralogist. Div. Mines, Dept. Natural Resources, CA |
| Sanidine | Greek sanis (-idos) = a board, a table in reference to the mineral's tabular habit |
| Salt | Latin sal which originated from the Greek for hals = the sea (see halite)
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| Samarskite | Vasilii Erafovich Samarski-Bykhovets (1803-1870), of the Russian Corps of Mining Engineers |
| Saponite | Latin sapo (-idos) = soap for its soaplike appearance |
| Sapphire | ancient name of uncertain origin; possibly Hebraic sappir and Sanskrit sanipruja; applied by the ancients to lazurite |
| Sassolite | Sasso, Tuscany, Italy where first observed, Greek lithos = stone |
| Searlesite | John W. Searles, Californian pioneer; Searles Lake, CA, named for him |
| Selenite | Greek selenites (lithos) = moon (stone) since it was supposed to wax and wane with the moon and/or it has moon-like white reflections |
| Sellaite | Quntino Sella (1827-1884), Italian mining engineer and mineralogist |
| Senarmonite | Henri Hureau de Sénarmont (1808-1862), French physicist and mineralogist, School of Mines, Paris, who first described the species |
| Sepiolite | Greek sepion = the bone of the cuttle-fish and lithos = stone since the bone of the cuttle-fish is light and porous like the mineral |
| Sericite | Greek for silky alluding to its silky luster |
| Serpentine | Latin serpens = snake because of the similar surface patterns |
| Shortite | Maxwell Naylor Short (1889-1952), American mineralogist, U of Arizona, and Greek lithos = stone |
| Siderite | Greek sideros = iron in reference to its composition |
| Sienna | locality at the town of Sienna in Tuscany, northern Italy |
| Silica | Latin silex = flint |
| Sillimanite | Professor Benjamin Silliman (1779-1864), American mineralogist, Yale |
| Slate | |
| Smectite | Greek smektis = fuller's earth from smechein = to wipe off, to cleanse because of its property of extracting grease from cloth (see Fuller's Earth) |
| Soda | possibly from the name of a mineral that occurs near Djebel es Soda, Libya. Alternatively, the Spanish soda (from the Arabian suvvad = a plant from the ash of which soda was obtained in Sicily and Spain), or from the medieval Latin sodanum = a remedy for headaches (from the Arabic suda = headache). |
| Soda ash | from soda and ash, originally prepared by evaporating the lixivium of wood ashes in iron pots (see potash) |
| Sodalite | from composition, Latin solidus = solid since it was a solid used in glassmaking (see soda ash) |
| Sodium sulfate | chemical name |
| Spessartine (garnet) | locality at Spessart in northwestern Bavaria, Germany |
| Sphalerite | Greek for trecherous or slippery since it was often mistaken for galena but yielded no lead |
| Sphene | Greek for wedge due to characteristic habit of the crystals |
| Spinel | Latin spinella = little thorn referring to its spine-shaped octahedral crystals |
| Spodumene | Greek spodoun = to reduce to ashes refers either to its ash-gray color or the ash-colored mass formed when heated before the blowpipe |
| Stassfurtite | locality at Stassfurt, Germany, where it is associated with potash. A.k.a. boracite |
| Staurolite | Greek stauros = a cross and lithos = stone because of its common cruciform twins |
| Steatite | Greek steatos = suet |
| Stibiconite | Greek stimmi and Latin stibium = antimony and Greek for powder or dust, because it often occurs as a powder |
| Stibnite | Greek stimmi and Latin stibium = old names for antimony |
| Strontianite | locality at Strontian, a small town in Argyllshire, Scotland |
| Suanite | locality at Suan County, Korea |
| Sulfur | Latin sulfur, an old name; akin to Sanskrit sulvere |
| Sulphohalite | from composition, a sulfate with the halogen elements Cl and F |
| Suzorite | locality at Suzor Township near Boucherville, Quebec, Canada (phlogopite mica) |
| Sylvite | old chemical name Sal digestivus Sylvii or digestive salt of Francois Sylvius de la Boë (1614-1672), Dutch chemist and physician of Leyden |
| Syngenite | Greek syn = with, together with, or related to in reference to its similarity to polyhalite |
| Szaibelyite | Stephan Szaibely (1777-1855), Hungarian mine surveyor of Rézbánya. A.k.a. ascherite |